July 20, 2017
The combination of amniotic membrane transplantation and antibiotic therapy leads to significantly better results than antibiotic therapy alone in eyes with bacterial keratitis, according to a study.
At Farabi Eye Hospital in Tehran, Iran, 49 eyes of 49 patients were treated with routine antibiotic therapy in combination with amniotic membrane transplantation, while 50 eyes of 50 patients received antibiotic therapy alone. Freshly prepared cefazolin 50 mg/mL and amikacin 14 mg/mL eye drops were administered every 2 hours in the first 3 days, followed by administration at the same interval during waking time only. Topical betamethasone 0.1% was also used four times a day and tapered over a 3- to 4-week period for all patients.